STRUCTURAL ELUCIDATION AND CONFORMATIONAL-ANALYSIS OF NEW LIGNAN BUTENOLIDES FROM THE LEAVES OF BUPLEURUM-SALICIFOLIUM

被引：16

作者：

ESTEVEZBRAUN, A

ESTEVEZREYES, R

GONZALEZ, AG

机构：

[1] C.P.N.O. Antonio González, Instituto Universitario de Bio-Orgánica, Universidad de La Laguna, Avda. Astrofísico Francisco Sánchez 2, La Laguna

来源：

TETRAHEDRON | 1994年 / 50卷 / 17期

关键词：

D O I：

10.1016/S0040-4020(01)90430-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

From the leaves of Bupleurum salicifolium two new benzylidene-benzyl-gamma-butyrolactone-type lignans salicifoline (2) and isosalicifoline (3) were isolated. The dibenzyl-butyrolactone (-)-epinortrachelogenin (1) was also isolated and it is the first time than this lignan has been obtained from a natural source. Their structures were determined by means of H-1 and C-13 NMR spectroscopic studies, including H-1-C-13 heteronuclear correlation (HETCOR), long range correlation spectra with inverse detection (HMBC), and chemical evidence. A study of the conformational analysis of these lignans using Molecular Mechanics Calculations is also included.

引用

页码：5203 / 5210

页数：8

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