A practical approach to enantiomerically pure cis-epoxides. Synthesis of (+)-disparlure

被引：21

作者：

SinhaBagchi, A

Sinha, SC

Keinan, E

机构：

[1] SCRIPPS RES INST, DEPT MOLEC BIOL, LA JOLLA, CA 92037 USA

[2] TECHNION ISRAEL INST TECHNOL, DEPT CHEM, IL-32000 HAIFA, ISRAEL

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 12期

关键词：

D O I：

10.1016/0957-4166(95)00405-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An efficient synthesis of (+)-disparlure has been achieved in >99.8% ee via the Sharpless asymmetric dihydroxylation followed by Mitsunobu inversion of one hydroxyl group and conversion of the resultant erythro diol to the cis epoxide.

引用

页码：2889 / 2892

页数：4

共 24 条

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