CRYSTALLOGRAPHIC ANALYSIS OF THE INHIBITION OF PORCINE PANCREATIC ELASTASE BY A PEPTIDYL BORONIC ACID - STRUCTURE OF A REACTION INTERMEDIATE

被引：53

作者：

TAKAHASHI, LH

RADHAKRISHNAN, R

ROSENFIELD, RE

MEYER, EF

机构：

[1] TEXAS A&M UNIV,DEPT BIOCHEM & BIOPHYS,COLLEGE STN,TX 77843

[2] TEXAS A&M UNIV,DEPT CHEM,COLLEGE STN,TX 77843

来源：

BIOCHEMISTRY | 1989年 / 28卷 / 19期

关键词：

D O I：

10.1021/bi00445a016

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：7610 / 7617

页数：8

共 48 条

[1] NORMAL-ALKYLBORONIC ACIDS AS BIFUNCTIONAL REVERSIBLE INHIBITORS OF ALPHA-CHYMOTRYPSIN [J].

ANTONOV, VK ;

IVANINA, TV ;

BEREZIN, IV ;

MARTINEK, K .

FEBS LETTERS, 1970, 7 (01) :23-&

[2] N-15 NMR-SPECTROSCOPY OF THE CATALYTIC-TRIAD HISTIDINE OF A SERINE PROTEASE IN PEPTIDE BORONIC ACID INHIBITOR COMPLEXES [J].

BACHOVCHIN, WW ;

WONG, WYL ;

FARRJONES, S ;

SHENVI, AB ;

KETTNER, CA .

BIOCHEMISTRY, 1988, 27 (20) :7689-7697

[3]

BACHOVCHIN WW, 1986, B MAGN RESON, V8, P189

[4] INTERACTION OF PEPTIDE BORONIC ACIDS WITH ELASTASE - CIRCULAR-DICHROISM STUDIES [J].

BERRY, SC ;

FINK, AL ;

SHENVI, AB ;

KETTNER, CA .

PROTEINS-STRUCTURE FUNCTION AND GENETICS, 1988, 4 (03) :205-210

[5] X-RAY CRYSTAL-STRUCTURE OF THE COMPLEX OF HUMAN-LEUKOCYTE ELASTASE (PMN ELASTASE) AND THE 3RD DOMAIN OF THE TURKEY OVOMUCOID INHIBITOR [J].

BODE, W ;

WEI, AZ ;

HUBER, R ;

MEYER, E ;

TRAVIS, J ;

NEUMANN, S .

EMBO JOURNAL, 1986, 5 (10) :2453-2458

[6] HUMAN-LEUKOCYTE AND PORCINE PANCREATIC ELASTASE - X-RAY CRYSTAL-STRUCTURES, MECHANISM, SUBSTRATE-SPECIFICITY, AND MECHANISM-BASED INHIBITORS [J].

BODE, W ;

MEYER, E ;

POWERS, JC .

BIOCHEMISTRY, 1989, 28 (05) :1951-1963

[7] SERINE PROTEASE MECHANISM - STRUCTURE OF AN INHIBITORY COMPLEX OF ALPHA-LYTIC PROTEASE AND A TIGHTLY BOUND PEPTIDE BORONIC ACID [J].

BONE, R ;

SHENVI, AB ;

KETTNER, CA ;

AGARD, DA .

BIOCHEMISTRY, 1987, 26 (24) :7609-7614

[8] STRUCTURAL-ANALYSIS OF SPECIFICITY - ALPHA-LYTIC PROTEASE COMPLEXES WITH ANALOGS OF REACTION INTERMEDIATES [J].

BONE, R ;

FRANK, D ;

KETTNER, CA ;

AGARD, DA .

BIOCHEMISTRY, 1989, 28 (19) :7600-7609

[9] GEOMETRICAL REACTION COORDINATES .2. NUCLEOPHILIC ADDITION TO A CARBONYL GROUP [J].

BURGI, HB ;

DUNITZ, JD ;

SHEFTER, E .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1973, 95 (15) :5065-5067

[10] AROMATIC-AROMATIC INTERACTION - A MECHANISM OF PROTEIN-STRUCTURE STABILIZATION [J].

BURLEY, SK ;

PETSKO, GA .

SCIENCE, 1985, 229 (4708) :23-28

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