TRANSFORMING GROWTH-FACTOR BETA(1) AS A PROGNOSTIC FACTOR IN PULMONARY ADENOCARCINOMA

被引：31

作者：

TAKANAMI, I

IMAMURA, T

HASHIZUME, T

KIKUCHI, K

YAMAMOTO, Y

KODAIRA, S

机构：

[1] TEIKYO UNIV,SCH MED,DEPT PATHOL,TOKYO 173,JAPAN

[2] KANAGAWA HOSP,NATL SANATORIUM,DEPT SURG,KANAGAWA,JAPAN

来源：

JOURNAL OF CLINICAL PATHOLOGY | 1994年 / 47卷 / 12期

关键词：

D O I：

10.1136/jcp.47.12.1098

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Aims-To evaluate the efficacy of transforming growth factor beta (TGF-beta) for the prognosis of pulmonary adenocarcinoma. Methods-TGF-beta was detected immunohistochemically using the avidin-biotin-peroxidase complex technique in resected pulmonary adenocarcinomas from 88 patients. Results-Of the 88 patients, 39 were TGF-beta negative and 45 TGF-beta positive. The five year survival rate was 56% for the TGF-beta negative and 16% for the TGF-beta positive group. Conclusions-TGF-beta can be used as a prognostic factor in pulmonary adenocarcinoma.

引用

页码：1098 / 1100

页数：3

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