HUMAN SEMINAL PLASMA SUPPRESSES THE CHEMILUMINESCENCE OF POLYMORPHONUCLEARS WITHOUT MODIFYING PHAGOCYTOSIS

被引：10

作者：

BOUVET, JP

DAZAMBUJA, S

ROUX, C

LEBRUN, L

PILLOT, J

机构：

[1] HOP HOTEL DIEU,FAC MED BROUSSAIS,HISTOL EMBRYOL LAB,F-75181 PARIS 04,FRANCE

[2] HOP ANTOINE BECLERE,SERV MICROBIOL,PARIS,FRANCE

来源：

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY | 1990年 / 23卷 / 02期

关键词：

chemiluminescence; oxygen radicals; phagocytosis; polymorphonuclears; seminal plasma;

D O I：

10.1111/j.1600-0897.1990.tb00673.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

ABSTRACT: The suppressive activity of human seminal plasma was confirmed on the luminol‐amplified chemiluminescent reaction of human polymorphonuclears. This suppression was found to be dose‐dependent and noncytotoxic. The responsible factor appeared to be a radical scavenger of low molecular weight, acting selectively on hydrogen peroxide. Correlation with glandular markers of semen indicated this molecule to have a prostatic origin. Neither crude seminal plasma nor this factor were found to suppress intracellular engulfment and killing of bacteria. This molecule seems to cooperate with the other semen antioxidants to protect sperm cells from extracellular oxygen radicals. 1990 Munksgaard

引用

页码：64 / 68

页数：5

共 21 条

[1] EFFECT OF HUMAN SEMINAL PLASMA ON TUMOR-ASSOCIATED IMMUNITY IN PATIENTS WITH ADENOCARCINOMA OF THE PROSTATE
ABLIN, RJ
BHATTI, RA
BUSH, IM
GUINAN, PD
[J]. JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 1980, 1 (5-6) : 337 - 345
[2] ABLIN RJ, 1984, PROTIDES BIOL FLUIDS, V32, P271
[3] ALEXANDER NJ, 1987, FERTIL STERIL, V47, P192
[4] ALLEN RC, 1986, METHOD ENZYMOL, V133, P449
[5] EVALUATION OF A FLUOROCHROME ASSAY FOR ASSESSING THE BACTERICIDAL ACTIVITY OF NEUTROPHILS IN HUMAN PHAGOCYTE DYSFUNCTIONS
BELLINATIPIRES, R
MELKI, SE
COLLETTO, GMDD
CARNEIROSAMPAIO, MMS
[J]. JOURNAL OF IMMUNOLOGICAL METHODS, 1989, 119 (02) : 189 - 196
[6] BOUVET JP, 1988, AM J REPROD IMMUNOL, V18, P87
[7] BOYUM A, 1968, SCAND J CLIN LAB INV, VS 21, P77
[8] HUMAN SEMINAL PLASMA INHIBITION OF ANTIBODY COMPLEMENT-MEDIATED KILLING AND OPSONIZATION OF NEISSERIA-GONORRHOEAE AND OTHER GRAM-NEGATIVE ORGANISMS
BROOKS, GF
LAMMEL, CJ
PETERSEN, BH
STITES, DP
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1981, 67 (05) : 1523 - 1531
[9] DAGLEY S, 1974, METHOD ENZYMAT AN, V3, P1562
[10] DECHATELET LR, 1982, J IMMUNOL, V129, P1589

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