HUMAN SEMINAL PLASMA SUPPRESSES THE CHEMILUMINESCENCE OF POLYMORPHONUCLEARS WITHOUT MODIFYING PHAGOCYTOSIS

被引:10
作者
BOUVET, JP
DAZAMBUJA, S
ROUX, C
LEBRUN, L
PILLOT, J
机构
[1] HOP HOTEL DIEU,FAC MED BROUSSAIS,HISTOL EMBRYOL LAB,F-75181 PARIS 04,FRANCE
[2] HOP ANTOINE BECLERE,SERV MICROBIOL,PARIS,FRANCE
来源
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY | 1990年 / 23卷 / 02期
关键词
chemiluminescence; oxygen radicals; phagocytosis; polymorphonuclears; seminal plasma;
D O I
10.1111/j.1600-0897.1990.tb00673.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
ABSTRACT: The suppressive activity of human seminal plasma was confirmed on the luminol‐amplified chemiluminescent reaction of human polymorphonuclears. This suppression was found to be dose‐dependent and noncytotoxic. The responsible factor appeared to be a radical scavenger of low molecular weight, acting selectively on hydrogen peroxide. Correlation with glandular markers of semen indicated this molecule to have a prostatic origin. Neither crude seminal plasma nor this factor were found to suppress intracellular engulfment and killing of bacteria. This molecule seems to cooperate with the other semen antioxidants to protect sperm cells from extracellular oxygen radicals. 1990 Munksgaard
引用
收藏
页码:64 / 68
页数:5
相关论文
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WOLFSON M, 1985, J IMMUNOL, V135, P2057