STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS .31. SYNTHESIS AND OPIOID ANTAGONIST POTENCIES OF NALTREXAMINE BIVALENT LIGANDS WITH CONFORMATIONALLY RESTRICTED SPACERS

被引：37

作者：

PORTOGHESE, PS ^{[1
]}

RONSISVALLE, G ^{[1
]}

LARSON, DL ^{[1
]}

TAKEMORI, AE ^{[1
]}

机构：

[1] UNIV MINNESOTA,SCH MED,SCH MED,DEPT PHARMACOL,MINNEAPOLIS,MN 55455

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1986年 / 29卷 / 09期

关键词：

D O I：

10.1021/jm00159a014

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1650 / 1653

页数：4

共 18 条

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[2] DIMERIC PENTAPEPTIDE ENKEPHALIN - A NOVEL PROBE OF DELTA OPIATE RECEPTORS
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[3] NARCOTIC ANTAGONISTIC POTENCY OF BIVALENT LIGANDS WHICH CONTAIN BETA-NALTREXAMINE - EVIDENCE FOR BRIDGING BETWEEN PROXIMAL RECOGNITION SITES
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[5] STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS .23. SYNTHESIS AND BIOLOGICAL EVALUATION OF 6-AMINO DERIVATIVES OF NALOXONE AND NALTREXONE
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[6] ABRUPT CHANGES IN VISUAL-STIMULATION ENHANCE PROCESSING OF FORM AND LOCATION INFORMATION
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[J]. PERCEPTION & PSYCHOPHYSICS, 1982, 32 (06): : 511 - 523
[7] LIPKOWSKI AW, 1982, POL J PHARMACOL PHAR, V34, P69
[8] DOUBLE-ENKEPHALINS - SYNTHESIS, ACTIVITY ON GUINEA-PIG ILEUM, AND ANALGESIC EFFECT
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[J]. PEPTIDES, 1982, 3 (04) : 697 - 700
[9] STEREOCHEMICAL STUDIES ON MEDICINAL AGENTS .29. STEREOSTRUCTURE - ACTIVITY RELATIONSHIP OF OPIOID AGONIST AND ANTAGONIST BIVALENT LIGANDS - EVIDENCE FOR BRIDGING BETWEEN VICINAL OPIOID RECEPTORS
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[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (09) : 1140 - 1141
[10] OPIOID AGONIST AND ANTAGONIST BIVALENT LIGANDS AS RECEPTOR PROBES
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