FULLY ACETYLATED CARBAMATE AND HYPOTENSIVE THIOCARBAMATE GLYCOSIDES FROM MORINGA-OLEIFERA

被引：129

作者：

FAIZI, S ^{[1
]}

SIDDIQUI, BS ^{[1
]}

SALEEM, R ^{[1
]}

SIDDIQUI, S ^{[1
]}

AFTAB, K ^{[1
]}

GILANI, AUH ^{[1
]}

机构：

[1] AGA KHAN UNIV,FAC HLTH SCI,DEPT PHARMACOL,KARACHI 74800,PAKISTAN

来源：

PHYTOCHEMISTRY | 1995年 / 38卷 / 04期

关键词：

MORINGA OLEIFERA; MORINGACEAE; SAHJNA; LEAVES; BIOASSAY-DIRECTED ISOLATION; THIOCARBAMATE; CARBAMATE AND NITRILE GLYCOSIDES; FULLY ACETYLATED SUGAR; 2D NMR; HYPOTENSIVE ACTIVITY;

D O I：

10.1016/0031-9422(94)00729-D

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Six new and three synthetically known glycosides have been isolated from the leaves of Moringa oleifera, employing a bioassay-directed isolation method on the ethanolic extract. Most of these compounds, bearing thiocarbamate, carbamate or nitrile groups, are fully acetylated glycosides, which are very rare in nature. Elucidation of the structures was made using chemical and spectroscopic methods, including 2D NMR techniques. Thiocarbamates showed hypotensive activity.

引用

页码：957 / 963

页数：7

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