DECREASED BENZODIAZEPINE RECEPTOR-BINDING IN PANIC DISORDER MEASURED BY IOMAZENIL-SPECT - A PRELIMINARY-REPORT

被引：73

作者：

SCHLEGEL, S ^{[1
]}

STEINERT, H ^{[1
]}

BOCKISCH, A ^{[1
]}

HAHN, K ^{[1
]}

SCHLOESSER, R ^{[1
]}

BENKERT, O ^{[1
]}

机构：

[1] UNIV MAINZ,DEPT NUCL MED,D-55131 MAINZ,GERMANY

来源：

EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE | 1994年 / 244卷 / 01期

关键词：

PANIC DISORDER; BENZODIAZEPINE RECEPTOR; IOMAZENIL; SPECT;

D O I：

10.1007/BF02279812

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Single photon emission tomography (SPECT) imaging of the central benzodiazepine receptor (BZr) became possible with the newly developed ligand I-123-IOMAZENIL. The BZr binding was investigated in ten patients with panic disorder (PP) compared to ten epileptic patients (EP). Panic patients had lower IOMAZENIL uptake rates in the frontal, occipital and temporal cortex than EP, indicating the involvement of the BZr complex in panic disorder.

引用

页码：49 / 51

页数：3

共 20 条

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