ATRIAL NATRIURETIC PEPTIDE-LIKE IMMUNOREACTIVITY IN ASTROCYTES OF PARENCHYMA AND GLIA LIMITANS OF THE CANINE BRAIN

被引：18

作者：

MCKENZIE, JC ^{[1
]}

机构：

[1] HOWARD UNIV,COLL MED,CANC RES CTR,WASHINGTON,DC 20059

来源：

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY | 1992年 / 40卷 / 08期

关键词：

ATRIAL NATRIURETIC PEPTIDE; BRAIN; ASTROGLIA; GLIA-LIMITANS; CEREBROVASCULAR REGULATION; IMMUNOHISTOCHEMISTRY; DOG;

D O I：

10.1177/40.8.1535643

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The Na+-regulating and vasoactive peptide hormone atrial natriuretic peptide (ANP) has been localized in cultured glial cells from neonatal rat brain but has not been reported in situ in adult brain. In the present study, immunohistochemical localization of ANP in astrocytes of adult canine brain was obtained using an antibody against rat ANF IV, a 25-amino acid fragment identical to low molecular weight brain ANP. ANP-like immunoreactivity was localized in widely dispersed astroglia throughout the canine brain, including Types I and II, in addition to some astrocytes of the glia limitans (GL).

引用

页码：1211 / 1222

页数：12

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