SELECTIVE THROMBOXANE SYNTHETASE INHIBITORS .4. 2-(1H-IMIDAZOL-1-YLMETHYL) CARBOXYLIC-ACIDS OF BENZO[B]FURAN, BENZO[B]THIOPHENE, INDOLE, AND NAPHTHALENE

被引：31

作者：

CROSS, PE ^{[1
]}

DICKINSON, RP ^{[1
]}

PARRY, MJ ^{[1
]}

RANDALL, MJ ^{[1
]}

机构：

[1] PFIZER CENT RES,SANDWICH CT13 9NJ,KENT,ENGLAND

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1986年 / 29卷 / 09期

关键词：

D O I：

10.1021/jm00159a013

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1643 / 1650

页数：8

共 14 条

[1] SELECTIVE THROMBOXANE SYNTHETASE INHIBITORS .2. 3-(1H-IMIDAZOL-1-YLMETHYL)-2-METHYL-1H-INDOLE-1-PROPANOIC ACID AND ANALOGS [J].

CROSS, PE ;

DICKINSON, RP ;

PARRY, MJ ;

RANDALL, MJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (03) :342-346

[2] SELECTIVE THROMBOXANE SYNTHETASE INHIBITORS .1. 1-[(ARYLOXY)ALKYL]-1H-IMIDAZOLES [J].

CROSS, PE ;

DICKINSON, RP ;

PARRY, MJ ;

RANDALL, MJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (10) :1427-1432

[3] SELECTIVE THROMBOXANE SYNTHETASE INHIBITORS .3. 1H-IMIDAZOL-1-YL-SUBSTITUTED BENZO[B]FURAN, BENZO[B]THIOPHENE, AND INDOLE-2-CARBOXYLIC AND INDOLE-3-CARBOXYLIC ACIDS [J].

CROSS, PE ;

DICKINSON, RP ;

PARRY, MJ ;

RANDALL, MJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (09) :1637-1643

[4]

CROSS PE, 1985, HETEROCYCLES, V23, P2391

[5]

CROSS PE, 1980, Patent No. 3001762

[6]

DANN O, 1973, ANNALEN, P1112

[7]

DMITRIENKO GI, 1979, HETEROCYCLES, V12, P1141

[8]

FU PP, 1974, TETRAHEDRON LETT, P3217

[9] HIGHLY SELECTIVE INHIBITORS OF THROMBOXANE SYNTHETASE .1. IMIDAZOLE DERIVATIVES [J].

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AKAHANE, K ;

MOMOSE, DI ;

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HAYASHI, M .

JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (10) :1139-1148

[10] ARACHIDONIC-ACID METABOLISM IN RAT BASOPHILIC LEUKEMIA (RBL-1) CELLS [J].

JAKSCHIK, BA ;

LEE, LH ;

SHUFFER, G ;

PARKER, CW .

PROSTAGLANDINS, 1978, 16 (05) :733-748

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