LISSENCEPHALY-1 IS ONE OF THE MOST CONSERVED PROTEINS BETWEEN MOUSE AND HUMAN, A SINGLE AMINO-ACID DIFFERENCE IN 410 RESIDUES

被引：23

作者：

PETERFY, M

GYURIS, T

BASU, R

TAKACS, L

机构：

[1] Amgen Inc., Thousand Oaks

来源：

GENE | 1994年 / 150卷 / 02期

关键词：

CDNA; MILLER-DIEKER SYNDROME; PAF ACETYLHYDROLASE;

D O I：

10.1016/0378-1119(94)90468-5

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The nucleotide (nt) sequence of the LIS-1 cDNA encoding the murine lissencephaly-1 (LIS-1) protein has been determined. The deduced protein shows a very high degree (99.8%) of homology with human LIS-1, having a single conservative amino acid (aa) change out of 410 aa and is identical to a subunit of bovine platelet-activating factor (PAF) acetylhydrolase.

引用

页码：415 / 416

页数：2

共 5 条

[1] THE NEUROGENETICS OF LISSENCEPHALY [J].