A NOVEL ONE-POT CONVERSION OF METHYL SULFONES TO SULFONAMIDES

被引：19

作者：

HUANG, HC

REINHARD, EJ

REITZ, DB

机构：

[1] G. D. Searle, Department of Medicinal Chemistry, St. Louis, MO 63198

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 39期

关键词：

D O I：

10.1016/0040-4039(94)85360-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot synthesis of sulfonamides from methyl sulfones has been developed. Treatment of methyl sulfones with base and trialkylboranes gave the corresponding rearranged sulfinic acid salts which were converted to sulfonamides during oxidative-amination workup.

引用

页码：7201 / 7204

页数：4