ANTIGEN-DETECTION IN INVASIVE ASPERGILLOSIS

被引：5

作者：

BURNIE, JP

机构：

[1] Department of Medical Microbiology, The Medical School, University of Manchester, Manchester, M13 9PT, Oxford Road

来源：

JOURNAL OF IMMUNOLOGICAL METHODS | 1991年 / 143卷 / 02期

关键词：

INVASIVE ASPERGILLOSIS; ANTIGEN DETECTION; REVERSE PASSIVE LATEX AGGLUTINATION; DOT-BLOT ASSAY;

D O I：

10.1016/0022-1759(91)90044-G

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The application of a reverse passive latex agglutination test and dot-blot assay are reported in the diagnosis of 50 proven cases of invasive aspergillosis and 28 suspected cases. At a latex titre cut off of greater than or equal to 1 in 8 the test had a sensitivity of 29.4%, specificity of 96.3% and efficiency of 41.4%. This was in sera taken when the diagnosis was first suggested. The sensitivity rose to 55.1% when sera with the maximum level of antigen were examined. The dot blot was more sensitive with 33.3% of cases being positive in the initial sera. This increased to 61.5% when the serum with the maximum antigen level was taken.

引用

页码：187 / 195

页数：9