METHIONINE PREVENTS NITROUS OXIDE-INDUCED TERATOGENICITY IN RAT EMBRYOS GROWN IN CULTURE

被引：33

作者：

FUJINAGA, M

BADEN, JM

机构：

[1] STANFORD UNIV, DEPT ANESTHESIA, STANFORD, CA 94305 USA

[2] VET AFFAIRS MED CTR, ANESTHESIOL SERV, PALO ALTO, CA USA

来源：

ANESTHESIOLOGY | 1994年 / 81卷 / 01期

关键词：

ANESTHETICS; GASES; NITROUS OXIDE; SYMPATHETIC NERVOUS SYSTEM; SYMPATHOMIMETICS; TOXICITY; TERATOGENICITY;

D O I：

10.1097/00000542-199407000-00025

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Background: Nitrous oxide (N2O)-induced teratogenicity in rats is commonly believed to be due to decreased tetrahydrofolate, which results in decreased DNA synthesis. The role of decreased methionine has been largely ignored as have the sympathomimetic effects of N2O.

引用

页码：184 / 189

页数：6

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