PHARMACOLOGICAL MANAGEMENT OF NEONATAL CEREBRAL-ISCHEMIA AND HEMORRHAGE - OLD AND NEW DIRECTIONS

被引：6

作者：

MILLER, VS ^{[1
]}

机构：

[1] UNIV TEXAS, SW MED SCH, DIV PEDIAT NEUROL, DALLAS, TX 75230 USA

来源：

JOURNAL OF CHILD NEUROLOGY | 1993年 / 8卷 / 01期

关键词：

D O I：

10.1177/088307389300800102

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

New developments in pharmacologic management of cerebral ischemia and hemorrhage are reviewed. A number of agents with diverse modes of action have now been shown to be neuroprotective in adult and neonatal animal models when administered either before or after a hypoxic-ischemic insult. As experience improves with these agents in hypoxic-ischemic injury and periventricular-intraventricular hemorrhage in human neonates, there is reason to be optimistic that effective neuroprotective strategies will soon be clinically available.

引用

页码：7 / 18

页数：12

共 166 条

[21] ELECTROPHYSIOLOGICAL EVIDENCE FOR ACTIVATION OF NMDA RECEPTORS AND ITS ANTAGONISM BY MK-801 IN CEREBRAL-ISCHEMIA [J].

DALKARA, T ;

TAN, E ;

ERDEMLI, G ;

ONUR, R ;

ZILELI, T .

BRAIN RESEARCH, 1990, 532 (1-2) :101-106

[22]

De Carolis S, 1988, Fetal Ther, V3, P224

[23]

DEREUCK JL, 1984, ACTA NEUROL SCAND, V70, P391

[24]

DIGIACOMO JE, 1992, BIOL NEONATE, V61, P25, DOI 10.1159/000243527

[25]

DONAT JF, 1978, MAYO CLIN PROC, V53, P437

[26]

DONN SM, 1981, LANCET, V2, P215

[27]

FINER NN, 1982, LANCET, V1, P1087

[28] SUPEROXIDE-DISMUTASE FOR THERAPEUTIC USE - CLINICAL-EXPERIENCE, DEAD ENDS AND HOPES [J].

FLOHE, L .

MOLECULAR AND CELLULAR BIOCHEMISTRY, 1988, 84 (02) :123-131

[29]

FLYNN CJ, 1989, BASIC NEUROCHEMISTRY, P783

[30] MK-801 PREVENTS HIPPOCAMPAL NEURODEGENERATION IN NEONATAL HYPOXIC-ISCHEMIC RATS [J].

FORD, LM ;

SANBERG, PR ;

NORMAN, AB ;

FOGELSON, MH .

ARCHIVES OF NEUROLOGY, 1989, 46 (10) :1090-1096

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