THE CHEMOTACTIC EFFECT OF PHLEBOTOMUS-DUBOSCQI (DIPTERA, PSYCHODIDAE) SALIVARY-GLAND LYSATES TO MURINE MONOCYTES

被引：21

作者：

ANJILI, CO

MBATI, PA

MWANGI, RW

GITHURE, JI

OLOBO, JO

ROBERT, LL

KOECH, DK

机构：

[1] KENYA GOVT MED RES CTR,BIOMED SCI RES CTR,NAIROBI,KENYA

[2] UNIV NAIROBI,DEPT ZOOL,NAIROBI,KENYA

[3] WALTER REED PROJECT,NAIROBI,KENYA

来源：

ACTA TROPICA | 1995年 / 60卷 / 02期

关键词：

PHLEBOTOMUS DUBOSCQI; SALIVARY GLAND LYSATE; BALB/C; MONOCYTE; CHEMOTAXIS;

D O I：

10.1016/0001-706X(95)00112-R

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

The possibility that salivary gland lysates of Phlebotomus duboscqi are able to attract vertebrate monocytes was investigated. In vitro studies showed that salivary gland lysates of P. duboscqi, the vector of Leishmania major in Kenya, are chemotactic to mouse peritoneal monocytes. This attraction of monocytes by vector salivary gland lysates may form part of the mechanisms through which sandfly saliva ensures successful parasitization of macrophages in a susceptible host by Leishmania parasites.

引用

页码：97 / 100

页数：4

共 13 条

[1] MODIFIED METHOD FOR CHEMOTAXIS UNDER AGAROSE [J].