ELECTRICAL RESPONSES OF SALIVARY-GLAND CELLS OF THE GASTROPOD MOLLUSK PHILINE-APERTA TO PUTATIVE NEUROTRANSMITTERS .2. OCTOPAMINE, 5-HT AND OTHER BIOGENIC-AMINES

被引：6

作者：

BARBER, A

机构：

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY | 1982年 / 73卷 / 02期

关键词：

D O I：

10.1016/0306-4492(82)90136-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Intracellular recordings were made from salivary gland cells of P. aperta. Salivary cell action potentials were produced in a dose-dependent manner in response to bath-application of octopamine, 5-hydroxytryptamine (5-HT) and certain related biogenic amines. Evidence that amines act on presynaptic receptors on nerve terminals rather than directly on gland cell receptors is presented. These receptors may serve to modulate salivary neuroglandular transmission. Octopamine and 5-HT action was reversibly blocked or reduced by the antagonists phentolamine, chlorpromazine, cyproheptidene, yohimbine, D-tubocurarine, hexamethonium and atropine.

引用

页码：361 / 367

页数：7

共 37 条

[1]

ALTRUP U, 1979, MALACOLOGIA, V18, P473

[2] LOCALIZATION OF MONOAMINE NERVE-FIBERS BY FORMALDEHYDE FLUORESCENCE HISTOCHEMISTRY IN POSTERIOR SALIVARY DUCT AND GLAND OF OCTOPUS-VULGARIS [J].