NOVEL, METAL-CATALYZED CARBONYLATION OF ACYCLIC ORGANIC-COMPOUNDS - THE REGIOSPECIFIC CARBONYLATION OF N,S-ACETALS

被引：31

作者：

KHUMTAVEEPORN, K ^{[1
]}

ALPER, H ^{[1
]}

机构：

[1] UNIV OTTAWA,DEPT CHEM,10 MARIE CURIE ST,OTTAWA K1N 6N5,ONTARIO,CANADA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 06期

关键词：

D O I：

10.1021/jo00085a034

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The rhodium(I) complex, [Rh(CO)2Cl]2, catalyzes the regiospecific carbonylation of N,S-acetals of structural type PhCH2SCH2NR1R2 to form PhCH2COSCH2NR1R2 in 68-92% isolated yields. Exclusive insertion of carbon monoxide occurs into the other sulfur-carbon bond of RSCH(Ph)-NR3R4 (R = PhCH2, n-C11H23) affording RSCOCH(Ph)NR3R4 in 46-83% yield.

引用

页码：1414 / 1417

页数：4

共 12 条

[11] REGIOSPECIFIC CARBONYLATION AND RING EXPANSION OF THIETANES AND OXETANES CATALYZED BY COBALT AND OR RUTHENIUM CARBONYLS [J].

WANG, MD ;

CALET, S ;

ALPER, H .

JOURNAL OF ORGANIC CHEMISTRY, 1989, 54 (01) :20-21

[12] REGIOSELECTIVE SYNTHESIS OF PIPERIDINONES BY METAL-CATALYZED RING EXPANSION CARBONYLATION REACTIONS - REMARKABLE COBALT AND OR RUTHENIUM CARBONYL CATALYZED REARRANGEMENT AND CYCLIZATION REACTIONS [J].

WANG, MD ;

ALPER, H .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (18) :7018-7024

← 1 2 →