A CONSONANT MODEL OF THE TRANSFER RNA-RIBOSOME COMPLEX DURING THE ELONGATION CYCLE OF TRANSLATION

被引：23

作者：

WOWER, J ^{[1
]}

ZIMMERMANN, RA ^{[1
]}

机构：

[1] UNIV MASSACHUSETTS, DEPT BIOCHEM, AMHERST, MA 01003 USA

来源：

BIOCHIMIE | 1991年 / 73卷 / 7-8期

关键词：

AFFINITY LABELING; CROSS-LINKING TECHNIQUES; TRANSFER RNA-RIBOSOME COMPLEX; PEPTIDYL TRANSFERASE CENTER; DECODING SITE;

D O I：

10.1016/0300-9084(91)90137-P

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chemical and photochemical affinity techniques have been used extensively to determine the positions of the tRNA binding sites on the Escherichia coli ribosome. Recent advances in our understanding of ribosome structure and function prompted us to critically review the data that have accumulated on tRNA-ribosome cross-links. As a result, we propose a new model of the tRNA-ribosome complex that accounts for nearly all of the pertinent evidence.

引用

页码：961 / 969

页数：9

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