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CHIRAL CAPILLARY HPLC AND HPLC-MS - NEW APPLICATIONS OF CHEMICALLY BONDED BETA-CYCLODEXTRIN AS STATIONARY-PHASE

被引：9
作者：
CABRERA, K
JUNG, M
KEMPTER, C
SCHURIG, V
机构：
[1] E MERCK AG, LAB CHROM 1, D-64293 DARMSTADT, GERMANY
[2] INST ORGAN CHEM, D-72076 TUBINGEN, GERMANY
来源：
FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY | 1995年 / 352卷 / 7-8期
关键词：
D O I：
10.1007/BF00323046
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Chemically bonded beta-cyclodextrin (ChiraDex(R)) has been packed into 0.25 mm i.d. capillaries and used for the enantiomer separation of several pharmaceuticals by capillary HPLC with UV and electrospray ionization (ESI) MS detection. While having several advantages over conventional HPLC, capillary HPLC yielded comparable results, e.g. with respect to resolution and sensitivity. The good compatibility to ESI-MS was demonstrated.
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页码：676 / 678
页数：3
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