STEREOSELECTIVE SYNTHESIS OF LONG-CHAIN POLYOLS BY SEQUENTIAL HOMOLOGATION OF ENALS WITH NONRACEMIC GAMMA-SILYLOXY ALLYLIC STANNANES AND DIRECTED HYDROXYLATION

被引：27

作者：

MARSHALL, JA

BEAUDOIN, S

LEWINSKI, K

机构：

[1] Department of Chemistry and Biochemistry, University of South Carolina, Columbia

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 22期

关键词：

D O I：

10.1021/jo00074a004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The nonracemic gamma-silyloxy allylic stannanes (S)-8 and (R)-8 add to the (R,R)-tartrate derived enals 7 and 24 to afford the adducts 9, 14, and 25. The bis-TBS derivatives 10, 15 and 22, upon hydroxylation with catalytic 0804-NMO, yield the differentially protected polyols 11, 16, and 23.

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页码：5876 / 5877

页数：2

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