THE INFLUENCE OF GRAVIDITY ON DOWNS-SYNDROME SCREENING WITH FREE BETA-HCG

被引：17

作者：

SPENCER, K

机构：

[1] Endocrine Unit, Clinical Biochemistry Department, Oldchurch Hospital, Romford, Essex

来源：

PRENATAL DIAGNOSIS | 1995年 / 15卷 / 01期

关键词：

ALPHA-FETOPROTEIN; HUMAN CHORIONIC GONADOTROPIN;

D O I：

10.1002/pd.1970150119

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Total human chorionic gonadotropin (hCG) levels have been shown in one previous small study to vary with gravidity. In order to establish if maternal serum free beta hCG was similarly affected, approximately 4500 pregnancies of varying gravidity were analysed. The results indicated that there was a 6 per cent higher median MOM in primigravid compared with multigravid women. The impact of such elevation in Down's syndrome screening programmes will be minimal.

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页码：87 / 89

页数：3

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