MAPPING THE DIFFERENTIAL-EFFECTS OF PROCAINE ON FREQUENCY AND AMPLITUDE OF RETICULARLY ELICITED HIPPOCAMPAL RHYTHMICAL SLOW ACTIVITY

被引：149

作者：

KIRK, IJ ^{[1
]}

MCNAUGHTON, N ^{[1
]}

机构：

[1] UNIV OTAGO,NEUROSCI RES CTR,DUNEDIN,NEW ZEALAND

来源：

HIPPOCAMPUS | 1993年 / 3卷 / 04期

关键词：

HIPPOCAMPAL RHYTHMICAL SLOW ACTIVITY; THETA-RHYTHM; MEDIAL SEPTUM; SUPRAMAMMILLARY NUCLEUS;

D O I：

10.1002/hipo.450030411

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Hippocampal rhythmical slow activity (RSA, theta) was elicited in urethanized rats by high-frequency stimulation in the reticular formation. The effects of procaine infusion (0.5 muL, 20% wt/vol) at various loci in the ascending system from pontine reticular formation to the medial septum/diagonal band area were investigated. It was found that procaine injected at points in the ascending system anterior to the supramamillary nucleus, in the region of the medial forebrain bundle or in the medial septum, reduced the amplitude of reticularly elicited RSA but had no effect on its frequency. Procaine injected at points in the ascending system from just anterior to the reticular formation stimulation site, up to, and including the supramamillary nucleus, reduced both the frequency and amplitude of reticularly elicited RSA. These results indicate that the frequency of reticularly elicited RSA is encoded in the supramamillary area, rather than in the medial septum/diagonal band as have previously been suggested.

引用

页码：517 / 526

页数：10

共 49 条

[21]

Klemm W R, 1976, Prog Neurobiol, V7, P197, DOI 10.1016/0301-0082(76)90007-1

[22]

Kocsis B., 1992, Society for Neuroscience Abstracts, V18, P4

[23] CARBACHOL-INDUCED EEG THETA-ACTIVITY IN HIPPOCAMPAL BRAIN-SLICES [J].