HYDROXYLATION OF DEBRISOQUINE USING PERFUSED LIVER ISOLATED FROM SPRAGUE DAWLEY AND DA RATS - COMPARISON WITH INVIVO RESULTS

被引：11

作者：

VINCENTVIRY, M

DESHAYES, S

MOTHE, O

SIEST, G

GALTEAU, MM

机构：

[1] CTR MED PREVENT LAB, 2 AVE DOYEN JACQUES PARISOT, F-54501 VANDOEUVRE LES NANCY, FRANCE

[2] CTR MEDICAMENT, CNRS, UA 597, F-54000 NANCY, FRANCE

来源：

JOURNAL OF PHARMACY AND PHARMACOLOGY | 1988年 / 40卷 / 10期

关键词：

D O I：

10.1111/j.2042-7158.1988.tb06997.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：694 / 700

页数：7

共 28 条

[1] COMPARATIVE EFFECT OF A SERIES OF HYPOLIPIDEMIC COMPOUNDS ON THE RELEASE OF ENZYMES FROM ISOLATED HEPATOCYTES [J].

AGUIAR, K ;

GALTEAU, MM ;

SIEST, G ;

FOURNEL, S ;

MAGDALOU, J .

BIOCHEMICAL PHARMACOLOGY, 1985, 34 (03) :379-380

[2] ANIMAL MODELING OF HUMAN POLYMORPHIC DRUG OXIDATION - THE METABOLISM OF DEBRISOQUINE AND PHENACETIN IN RAT INBRED STRAINS [J].

ALDABBAGH, SG ;

IDLE, JR ;

SMITH, RL .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1981, 33 (03) :161-164

[3] RELATION BETWEEN DRUG ELIMINATION KINETICS IN INTACT ANIMALS AND ISOLATED PERFUSED LIVER SYSTEMS - PHENYLBUTAZONE [J].

BAHR, CV ;

SJOQVIST, F ;

LEVY, G .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1970, 22 (11) :867-&

[4] LIVER PERFUSION TECHNIQUE USING INEXPENSIVE NON-BINDING MEDIUM FOR 1ST-PASS METABOLISM STUDIES OF DRUGS [J].

BEAUBIEN, AR ;

TRYPHONAS, L ;

PAKUTS, AP ;

MACCONAILL, M ;

COMBLEY, HA .

JOURNAL OF PHARMACOLOGICAL METHODS, 1979, 2 (03) :213-221

[5] TEMPERATURE EFFECTS ON RADIOCOLLOID UPTAKE BY THE ISOLATED RAT LIVER [J].

BRAUER, RW ;

HOLLOWAY, RJ ;

LEONG, GF .

AMERICAN JOURNAL OF PHYSIOLOGY, 1957, 189 (01) :24-30

[6]

DICK B, 1982, SCHWEIZ MED WSCHR, V112, P1061

[7]

DISTLERATH LM, 1985, J BIOL CHEM, V260, P9057

[8] POLYMORPHISMS OF OXIDATION AT CARBON CENTERS OF DRUGS AND THEIR CLINICAL SIGNIFICANCE [J].

IDLE, JR ;

SMITH, RL .

DRUG METABOLISM REVIEWS, 1979, 9 (02) :301-317

[9] COMPARATIVE PHARMACOGENETICS OF SPARTEINE AND DEBRISOQUINE [J].

INABA, T ;

VINKS, A ;

OTTON, SV ;

KALOW, W .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1983, 33 (03) :394-399

[10] REDUCTIVE DRUG-METABOLISM IN ISOLATED PERFUSED RAT-LIVER UNDER RESTRICTED OXYGEN-SUPPLY [J].

JONENKERN, R ;

JONEN, HG ;

SCHUPP, RR ;

MINCK, K ;

KAHL, GF ;

NETTER, KJ .

XENOBIOTICA, 1978, 8 (05) :271-280

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