2 UNIQUE PENTACYCLIC STEROIDS WITH CIS C/D RING JUNCTION FROM XESTOSPONGIA-BERGQUISTIA FROMONT, POWERFUL INHIBITORS OF HISTAMINE-RELEASE

被引：64

作者：

SHOJI, N

UMEYAMA, A

SHIN, K

TAKEDA, K

ARIHARA, S

KOBAYASHI, J

TAKEI, M

机构：

[1] UNIV TOKUSHIMA,FAC PHARMACEUT SCI,TOKUSHIMA 770,JAPAN

[2] HOKKAIDO UNIV,FAC PHARMACEUT SCI,KITA KU,SAPPORO,HOKKAIDO 060,JAPAN

[3] LA JOLLA INST ALLERGY & IMMUNOL,LA JOLLA,CA 92937

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 11期

关键词：

D O I：

10.1021/jo00037a009

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Xestobergsterol A (1) (23S-16-beta,23-cyclo-3-alpha,6-alpha,7-beta,23-tetrahydroxy-5-alpha,14-beta-cholestan-15-one) and B (2) (23S-16-beta,23-cyclo-1-beta,2-beta,3-alpha,6-alpha,7-beta,23-hexahydroxy-5-alpha, 14-beta-cholestan-15-one), potent inhibitors of histamine release from rat mast cells induced by anti-IgE, are the first report of steroids with both the C-16/C23 bond and cis C/D ring junction.

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页码：2996 / 2997

页数：2

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