Carotid intima-media thickness and cardiovascular risk

被引:13
作者
Mookadam, Farouk [1 ]
Tanasunont, Weerawat [1 ]
Jalal, Uzma [1 ]
Mookadam, Martina [1 ]
Wilansky, Susan [1 ]
机构
[1] Mayo Clin Scottsdale, Dept Cardiovasc Dis, Scottsdale, AZ 85259 USA
关键词
atherosclerosis; cardiovascular risk; carotid intima-media thickness; screening;
D O I
10.2217/FCA.11.2
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cardiovascular disease is the primary cause of death in most developed nations. Identifying an individual's cardiovascular risk remains a challenge. Traditional coronary-risk stratification is based on cardiovascular risk factors using risk score systems, which may not reliably identify atherosclerosis in asymptomatic individuals. Carotid intima-media thickness measured by ultrasonography is a noninvasive, wellvalidated tool that has been used as a surrogate for clinical coronary events. Carotid intima-media thickness has demonstrable utility as an independent predictor of future cardiovascular events. Recent data have improved our understanding of its application as a screening tool for cardiovascular disease.
引用
收藏
页码:173 / 182
页数:10
相关论文
共 40 条
[1]  
[Anonymous], 2002, LANCET, V360, P7
[2]   Effects of fosinopril and pravastatin on cardiovascular events in subjects with microalbuminuria [J].
Asselbergs, FW ;
Diercks, GFH ;
Hillege, HL ;
van Boven, AJ ;
Janssen, WMT ;
Voors, AA ;
de Zeeuw, D ;
de Jong, PE ;
van Veldhuisen, DJ ;
van Gilst, WH .
CIRCULATION, 2004, 110 (18) :2809-2816
[3]  
Baguet JP, 2009, VASC HEALTH RISK MAN, V5, P175
[4]   Intensive lipid lowering may reduce progression of carotid atherosclerosis within 12 months of treatment: the METEOR study [J].
Bots, M. L. ;
Palmer, M. K. ;
Dogan, S. ;
Plantinga, Y. ;
Raichlen, J. S. ;
Evans, G. W. ;
O'Leary, D. H. ;
Grobbee, D. E. ;
Crouse, J. R., III .
JOURNAL OF INTERNAL MEDICINE, 2009, 265 (06) :698-707
[5]  
Chambless LE, 2000, AM J EPIDEMIOL, V151, P478
[6]   Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels - Results of AFCAPS/TexCAPS [J].
Downs, JR ;
Clearfield, M ;
Weis, S ;
Whitney, E ;
Shapiro, DR ;
Beere, PA ;
Langendorfer, A ;
Stein, EA ;
Kruyer, W ;
Gotto, AM .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 279 (20) :1615-1622
[7]   Effect of Statins Alone Versus Statins Plus Ezetimibe on Carotid Atherosclerosis in Type 2 Diabetes [J].
Fleg, Jerome L. ;
Mete, Mihriye ;
Howard, Barabara V. ;
Umans, Jason G. ;
Roman, Mary J. ;
Ratner, Robert E. ;
Silverman, Angela ;
Galloway, James M. ;
Henderson, Jeffrey A. ;
Weir, Matthew R. ;
Wilson, Charlton ;
Stylianou, Mario ;
Howard, Wm. James .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2008, 52 (25) :2198-2205
[8]  
Greenland P, 2000, CIRCULATION, V101, P723
[9]   Low-dose metoprolol CR/XL and fluvastatin slow progression of carotid intima-media thickness -: Main results from the β-blocker cholesterol-lowering asymptomatic plaque study (BCAPS) [J].
Hedblad, B ;
Wikstrand, J ;
Janzon, L ;
Wedel, H ;
Berglund, G .
CIRCULATION, 2001, 103 (13) :1721-1726
[10]   Comparison between measures of atherosclerosis and risk of stroke - The Rotterdam Study [J].
Hollander, M ;
Hak, AE ;
Koudstaal, PJ ;
Bots, ML ;
Grobbee, DE ;
Hofman, A ;
Witteman, JCM ;
Breteler, MMB .
STROKE, 2003, 34 (10) :2367-2372