INHALATION PHARMACOKINETICS - EVALUATING SYSTEMIC EXTRACTION, TOTAL INVIVO METABOLISM, AND THE TIME COURSE OF ENZYME-INDUCTION FOR INHALED STYRENE IN RATS BASED ON ARTERIAL BLOOD - INHALED AIR CONCENTRATION RATIOS

被引：54

作者：

ANDERSEN, ME ^{[1
]}

GARGAS, ML ^{[1
]}

RAMSEY, JC ^{[1
]}

机构：

[1] DOW CHEM USA,TOXICOL RES LAB,MIDLAND,MI 48640

来源：

TOXICOLOGY AND APPLIED PHARMACOLOGY | 1984年 / 73卷 / 01期

关键词：

D O I：

10.1016/0041-008X(84)90065-6

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：176 / 187

页数：12

共 19 条

[1] ANDERSEN ME, 1981, NEUROBEH TOXICOL TER, V3, P383
[2] USE OF INHALATION TECHNIQUES TO ASSESS THE KINETIC CONSTANTS OF 1,1-DICHLOROETHYLENE METABOLISM
ANDERSEN, ME
GARGAS, ML
JONES, RA
JENKINS, LJ
[J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 1979, 47 (02) : 395 - 409
[3] DETERMINATION OF THE KINETIC CONSTANTS FOR METABOLISM OF INHALED TOXICANTS INVIVO USING GAS UPTAKE MEASUREMENTS
ANDERSEN, ME
GARGAS, ML
JONES, RA
JENKINS, LJ
[J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 1980, 54 (01) : 100 - 116
[4] RECENT ADVANCES IN METHODOLOGY AND CONCEPTS FOR CHARACTERIZING INHALATION PHARMACOKINETIC PARAMETERS IN ANIMALS AND MAN
ANDERSEN, ME
[J]. DRUG METABOLISM REVIEWS, 1982, 13 (05) : 799 - 826
[5] A PHYSIOLOGICALLY BASED TOXICOKINETIC DESCRIPTION OF THE METABOLISM OF INHALED GASES AND VAPORS - ANALYSIS AT STEADY-STATE
ANDERSEN, ME
[J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 1981, 60 (03) : 509 - 526
[6] METHOTREXATE PHARMACOKINETICS
BISCHOFF, KB
DEDRICK, RL
ZAHARKO, DS
LONGSTRETH, JA
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1971, 60 (08) : 1128 - +
[7] METABOLISM OF INHALED BROMINATED HYDROCARBONS - VALIDATION OF GAS UPTAKE RESULTS BY DETERMINATION OF A STABLE METABOLITE
GARGAS, ML
ANDERSEN, ME
[J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 1982, 66 (01) : 55 - 68
[8] Hilderbrand R L, 1981, Fundam Appl Toxicol, V1, P403, DOI 10.1016/S0272-0590(81)80017-6
[9] REVIEW OF THE APPLICATIONS OF PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING
HIMMELSTEIN, KJ
LUTZ, RJ
[J]. JOURNAL OF PHARMACOKINETICS AND BIOPHARMACEUTICS, 1979, 7 (02): : 127 - 145
[10] KARBOWSKI RJ, 1980, 19TH ANN M SOC TOX W

← 1 2 →