DIACETONE GLUCOSE ARCHITECTURE AS A CHIRALITY TEMPLATE .2. VERSATILE SYNTHON FOR THE CHIRAL DEUTERIUM LABELING AND SYNTHESIS OF ALL DIASTEREOISOMERS OF CHIRALLY MONODEUTERATED GLYCEROL

被引：20

作者：

KAKINUMA, K

IIHAMA, Y

TAKAGI, I

OZAWA, K

YAMAUCHI, N

IMAMURA, N

ESUMI, Y

URAMOTO, M

机构：

[1] Department of Chemistry, Tokyo Institute of Technology O-okayama, Meguro-ku, Tokyo

[2] Laboratory of Chemistry for Natural Products, Tokyo Institute of Technology O-okayama, Meguro-ku, Tokyo

[3] Institute of Physical and Chemical Research (RIKEN) Wako-shi, Saitama

来源：

TETRAHEDRON | 1992年 / 48卷 / 18期

关键词：

CHIRALITY TEMPLATE; DIACETONE GLUCOSE; LABELED COMPOUND; CHIRALLY MONODEUTERATED GLYCEROL;

D O I：

10.1016/S0040-4020(01)92267-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chirally deuterated ethylene oxide derivatives attached to a diacetone glucose template were developed as new versatile synthons for chiral deuterium labeling. All four diastereoisomers of chirally monodeuterated glycerol were also synthesized by chirality transcription from the same template.

引用

页码：3763 / 3774

页数：12

共 19 条

[1] BRANCHED-CHAIN SUGARS .15. THE CRYSTAL-STRUCTURE OF 3-C-[(R)-(1-HYDROXY-2-PHTHALIMIDOETHYL)]-1,2-5,6-DI-O-ISOPROPYLIDENE-ALPHA-D-ALLOFURANOSE AND RELATED STUDIES [J].