AMINE ASSISTED ENZYMATIC ESTERIFICATION OF 1,2-DIOL MONOTOSYLATES

被引：25

作者：

BOAZ, NW

ZIMMERMAN, RL

机构：

[1] Eastman Fine Chemicals, Eastman Kodak Company, Rochester

来源：

TETRAHEDRON-ASYMMETRY | 1994年 / 5卷 / 02期

关键词：

D O I：

10.1016/S0957-4166(00)86160-1

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The enzymatic esterification of 1,2-diol monotosylates in organic solvent under standard conditions often fails to achieve the desired 50% conversion due to enzyme inactivation by acidic contaminants. The inclusion of an amine affords rapid conversion to 50% and provides enhanced enantioselectivity.

引用

页码：153 / 156

页数：4

共 13 条

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