MINIATURE ELECTROCHEMICAL GLUCOSE BIOSENSORS

被引：22

作者：

KOUDELKAHEP, M

STRIKE, DJ

DEROOIJ, NF

机构：

[1] Institute of Microtechnology, University of Neuchâtel, 2000 Neuchâtel

来源：

ANALYTICA CHIMICA ACTA | 1993年 / 281卷 / 03期

基金：

美国国家科学基金会;

关键词：

BIOSENSORS; FLOW INJECTION; ENZYMES; GLUCOSE BIOSENSOR; GLUCOSE OXIDASE;

D O I：

10.1016/0003-2670(93)85003-3

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Glucose-oxidase-based sensors were realized using three techniques of immobilizing thin layers of enzyme over a three-thin-film electrode transducer. Sensors with chemically crosslinked membranes, completed by an outer diffusion-limiting membrane, were characterized with consideration of the basic requirements of an implantable device. Thus, e.g. a negligible loss of the activity was observed when the sensors were sterilized by a 2.5 MRad dose of gamma radiation. On the other hand, the sensors with the electrochemically deposited membranes were particularly suitable, e.g. with respect to response time, etc., for flow-injection analysis measurements.

引用

页码：461 / 466

页数：6