CUTANEOUS LEISHMANIASIS - REVIEW OF 59 CASES SEEN AT THE NATIONAL-INSTITUTES-OF-HEALTH

被引:79
作者
MELBY, PC
KREUTZER, RD
MCMAHONPRATT, D
GAM, AA
NEVA, FA
机构
[1] YOUNGSTOWN STATE UNIV, DEPT BIOL, YOUNGSTOWN, OH 44555 USA
[2] NIAID, PARASIT DIS LAB, BETHESDA, MD 20892 USA
[3] YALE UNIV, SCH MED, DEPT EPIDEMIOL & PUBL HLTH, NEW HAVEN, CT 06510 USA
关键词
D O I
10.1093/clind/15.6.924
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Fifty-nine cases of cutaneous leishmaniasis seen at the National Institutes of Health in Bethesda, Maryland, are reviewed. The group of patients involved was unique in that the majority were American civilians, their disease was acquired in many different endemic areas of the world, and their illnesses represented all points on the clinical spectrum of cutaneous disease. The majority of American patients acquired leishmaniasis while engaging in activities related to their occupations. Cutaneous disease acquired in the New World usually consisted of one or two lesions, while multiple lesions often characterized Old World infections with Leishmania major. Patients with chronic relapsing or diffuse cutaneous leishmaniasis were native to endemic areas and were infected at an early age. Even the localized form of cutaneous leishmaniasis was often extensive and difficult to treat. Diagnosis with culture and identification of the parasite to the subspecies level is instrumental in the selection of optimal therapy. Cutaneous leishmaniasis may be encountered increasingly often in the United States because of the frequent international travel of U.S. residents and the influx of immigrants from endemic areas of the world.
引用
收藏
页码:924 / 937
页数:14
相关论文
共 103 条
[81]   A HISTOLOGICAL CLASSIFICATION OF MUCOCUTANEOUS LEISHMANIASIS IN BRAZIL AND ITS CLINICAL-EVALUATION [J].
RIDLEY, DS ;
MARSDEN, PD ;
CUBA, CC ;
BARRETO, AC .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1980, 74 (04) :508-514
[82]   PATHOGENESIS OF CUTANEOUS LEISHMANIASIS [J].
RIDLEY, DS .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1979, 73 (02) :150-160
[83]   EFFICACY OF KETOCONAZOLE AGAINST LEISHMANIA-BRAZILIENSIS-PANAMENSIS CUTANEOUS LEISHMANIASIS [J].
SAENZ, RE ;
PAZ, H ;
BERMAN, JD .
AMERICAN JOURNAL OF MEDICINE, 1990, 89 (02) :147-155
[84]  
Sampaio R N, 1985, Lancet, V1, P1097
[85]  
Sampaio R. N., 1985, Revista da Sociedade Brasileira de Medicina Tropical, V18, P273, DOI 10.1590/S0037-86821985000400015
[86]  
SAMPAIO S A P, 1971, International Journal of Dermatology, V10, P179, DOI 10.1111/j.1365-4362.1971.tb01694.x
[87]   MUCOSAL DISEASE CAUSED BY LEISHMANIA-BRAZILIENSIS-GUYANENSIS [J].
SANTRICH, C ;
SEGURA, I ;
ARIAS, AL ;
SARAVIA, NG .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1990, 42 (01) :51-55
[88]   MUCOCUTANEOUS LEISHMANIASIS IN COLOMBIA - LEISHMANIA-BRAZILIENSIS SUBSPECIES DIVERSITY [J].
SARAVIA, NG ;
HOLGUIN, AF ;
MCMAHONPRATT, D ;
DALESSANDRO, A .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1985, 34 (04) :714-720
[89]  
Senekjie Harry A., 1943, AMER JOUR TROP MED, V23, P523
[90]   DISSEMINATED CUTANEOUS LEISHMANIASIS [J].
SHARMA, VK ;
KAUR, S ;
MAHAJAN, RC ;
JOSHI, K ;
KUMAR, B .
INTERNATIONAL JOURNAL OF DERMATOLOGY, 1989, 28 (04) :261-262