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APOPTOSIS - BIOCHEMICAL EVENTS AND RELEVANCE TO CANCER-CHEMOTHERAPY

被引：277
作者：
SEN, S
DINCALCI, M
机构：
来源：
FEBS LETTERS | 1992年 / 307卷 / 01期
关键词：
ANTICANCER AGENT; BCL-2; CALCIUM; CELL CYCLE PHASE; P34CDC2; P53; PROGRAMMED CELL DEATH; REGULATION; SULFATED GLYCOPROTEIN;
D O I：
10.1016/0014-5793(92)80914-3
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Two distinct pathways for cell death exist. Compared to necrotic death, physiological or apoptotic cell death is an active suicidal process that consists of a cascade of well-regulated synthetic events. Participation of specific genes in apoptosis, and its possible molecular regulation, are considered in order to investigate the mechanism of cell death induced by some cancer chemotherapeutic agents.
引用
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页码：122 / 127
页数：6
相关论文
共 89 条
[1]  
ALNEMRI ES, 1992, CANCER RES, V52, P491
[2]  
ARENDS MJ, 1990, AM J PATHOL, V136, P593
[3]   CELLS WITHOUT GROWTH-FACTORS COMMIT SUICIDE [J].
BARNES, DM .
SCIENCE, 1988, 242 (4885) :1510-1511
[4]   ACTIVATION OF PROGRAMMED CELL-DEATH (APOPTOSIS) BY CISPLATIN, OTHER ANTICANCER DRUGS, TOXINS AND HYPERTHERMIA [J].
BARRY, MA ;
BEHNKE, CA ;
EASTMAN, A .
BIOCHEMICAL PHARMACOLOGY, 1990, 40 (10) :2353-2362
[5]   THE RELATION OF PROGRAMMED CELL-DEATH TO DEVELOPMENT AND REPRODUCTION - COMPARATIVE STUDIES AND AN ATTEMPT AT CLASSIFICATION [J].
BEAULATON, J ;
LOCKSHIN, RA .
INTERNATIONAL REVIEW OF CYTOLOGY-A SURVEY OF CELL BIOLOGY, 1982, 79 :215-235
[6]   INDUCTION OF THE TRPM-2 GENE IN CELLS UNDERGOING PROGRAMMED DEATH [J].
BUTTYAN, R ;
OLSSON, CA ;
PINTAR, J ;
CHANG, CS ;
BANDYK, M ;
NG, PY ;
SAWCZUK, IS .
MOLECULAR AND CELLULAR BIOLOGY, 1989, 9 (08) :3473-3481
[7]   CASCADE INDUCTION OF C-FOS, C-MYC, AND HEAT-SHOCK 70K TRANSCRIPTS DURING REGRESSION OF THE RAT VENTRAL PROSTATE-GLAND [J].
BUTTYAN, R ;
ZAKERI, Z ;
LOCKSHIN, R ;
WOLGEMUTH, D .
MOLECULAR ENDOCRINOLOGY, 1988, 2 (07) :650-657
[8]  
CHATTERJEE S, 1990, CANCER RES, V50, P2713
[9]  
CHENG J, 1992, CANCER RES, V52, P222
[10]   TOPOISOMERAS-SPECIFIC DRUG SENSITIVITY IN RELATION TO CELL-CYCLE PROGRESSION [J].
CHOW, KC ;
ROSS, WE .
MOLECULAR AND CELLULAR BIOLOGY, 1987, 7 (09) :3119-3123
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