APOPTOSIS - BIOCHEMICAL EVENTS AND RELEVANCE TO CANCER-CHEMOTHERAPY

被引：277

作者：

SEN, S

DINCALCI, M

机构：

来源：

FEBS LETTERS | 1992年 / 307卷 / 01期

关键词：

ANTICANCER AGENT; BCL-2; CALCIUM; CELL CYCLE PHASE; P34CDC2; P53; PROGRAMMED CELL DEATH; REGULATION; SULFATED GLYCOPROTEIN;

D O I：

10.1016/0014-5793(92)80914-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two distinct pathways for cell death exist. Compared to necrotic death, physiological or apoptotic cell death is an active suicidal process that consists of a cascade of well-regulated synthetic events. Participation of specific genes in apoptosis, and its possible molecular regulation, are considered in order to investigate the mechanism of cell death induced by some cancer chemotherapeutic agents.

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页码：122 / 127

页数：6

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