DETERMINATION OF ADENOASSOCIATED VIRUS REP68 AND REP78 BINDING-SITES BY RANDOM SEQUENCE OLIGONUCLEOTIDE SELECTION

被引：53

作者：

CHIORINI, JA ^{[1
]}

YANG, L ^{[1
]}

SAFER, B ^{[1
]}

KOTIN, RM ^{[1
]}

机构：

[1] NHLBI,MOLEC HEMATOL BRANCH,BETHESDA,MD 20892

来源：

JOURNAL OF VIROLOGY | 1995年 / 69卷 / 11期

关键词：

D O I：

10.1128/JVI.69.11.7334-7338.1995

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

To further define the canonical binding site for the P-5-promoted Rep proteins of the adeno-associated virus, a modified random oligonucleotide selection procedure was performed, using purified recombinant Rep protein. These results may explain the effects of Rep on cellular gene expression.

引用

页码：7334 / 7338

页数：5

共 19 条

[11] SITE-SPECIFIC INTEGRATION BY ADENOASSOCIATED VIRUS
KOTIN, RM
SINISCALCO, M
SAMULSKI, RJ
ZHU, XD
HUNTER, L
LAUGHLIN, CA
MCLAUGHLIN, S
MUZYCZKA, N
ROCCHI, M
BERNS, KI
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (06) : 2211 - 2215
[12] CHARACTERIZATION OF A PREFERRED SITE ON HUMAN CHROMOSOME-19Q FOR INTEGRATION OF ADENOASSOCIATED VIRUS-DNA BY NONHOMOLOGOUS RECOMBINATION
KOTIN, RM
LINDEN, RM
BERNS, KI
[J]. EMBO JOURNAL, 1992, 11 (13) : 5071 - 5078
[13] POSITIVE AND NEGATIVE AUTOREGULATION OF THE ADENOASSOCIATED VIRUS TYPE-2 GENOME
LABOW, MA
HERMONAT, PL
BERNS, KI
[J]. JOURNAL OF VIROLOGY, 1986, 60 (01) : 251 - 258
[14] CONFORMATION TAKES PRECEDENCE OVER SEQUENCE IN ADENO-ASSOCIATED VIRUS-DNA REPLICATION
LEFEBVRE, RB
RIVA, S
BERNS, KI
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1984, 4 (07) : 1416 - 1419
[15] INTERACTION OF THE ADENOASSOCIATED VIRUS REP PROTEIN WITH A SEQUENCE WITHIN THE A-PALINDROME OF THE VIRAL TERMINAL REPEAT
MCCARTY, DM
RYAN, JH
ZOLOTUKHIN, S
ZHOU, XH
MUZYCZKA, N
[J]. JOURNAL OF VIROLOGY, 1994, 68 (08) : 4998 - 5006
[16] IDENTIFICATION OF LINEAR DNA-SEQUENCES THAT SPECIFICALLY BIND THE ADENOASSOCIATED VIRUS REP PROTEIN
MCCARTY, DM
PEREIRA, DJ
ZOLOTUKHIN, I
ZHOU, XH
RYAN, JH
MUZYCZKA, N
[J]. JOURNAL OF VIROLOGY, 1994, 68 (08) : 4988 - 4997
[17] DEFINING THE SEQUENCE SPECIFICITY OF DNA-BINDING PROTEINS BY SELECTING BINDING-SITES FROM RANDOM-SEQUENCE OLIGONUCLEOTIDES - ANALYSIS OF YEAST GCN4 PROTEIN
OLIPHANT, AR
BRANDL, CJ
STRUHL, K
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1989, 9 (07) : 2944 - 2949
[18] SHELLING AN, 1994, GENE THER, V2, P1
[19] ADENOASSOCIATED VIRUS (AAV) REP PROTEINS MEDIATE COMPLEX-FORMATION BETWEEN AAV DNA AND ITS INTEGRATION SITE IN HUMAN DNA
WEITZMAN, MD
KYOSTIO, SRM
KOTIN, RM
OWENS, RA
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (13) : 5808 - 5812

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