THE BASIC SCIENCE OF GENE-THERAPY

被引:1497
作者
MULLIGAN, RC [1 ]
机构
[1] MIT, DEPT BIOL, CAMBRIDGE, MA 02142 USA
关键词
D O I
10.1126/science.8493530
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The development over the past decade of methods for delivering genes to mammalian cells has stimulated great interest in the possibility of treating human disease by gene-based therapies. However, despite substantial progress, a number of key technical issues need to be resolved before gene therapy can be safely and effectively applied in the clinic. Future technological developments, particularly in the areas of gene delivery and cell transplantion, will be critical for the successful practice of gene therapy.
引用
收藏
页码:926 / 932
页数:7
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