DOSE-RELATED KINETICS OF ASPIRIN - PRESYSTEMIC ACETYLATION OF PLATELET CYCLOOXYGENASE

被引：498

作者：

PEDERSEN, AK ^{[1
]}

FITZGERALD, GA ^{[1
]}

机构：

[1] VANDERBILT UNIV, DIV CLIN PHARMACOL, NASHVILLE, TN 37232 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 1984年 / 311卷 / 19期

关键词：

D O I：

10.1056/NEJM198411083111902

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1206 / 1211

页数：6

共 34 条

[11] THROMBOXANES - NEW GROUP OF BIOLOGICALLY-ACTIVE COMPOUNDS DERIVED FROM PROSTAGLANDIN ENDOPEROXIDES [J].

HAMBERG, M ;

SVENSSON, J ;

SAMUELSSON, B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (08) :2994-2998

[12] INFLUENCE OF ROUTE OF ADMINISTRATION ON AREA UNDER PLASMA CONCENTRATION-TIME CURVE [J].

HARRIS, PA ;

RIEGELMA.S .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1969, 58 (01) :71-&

[13] RECOVERY OF ENDOTHELIAL CELL PROSTACYCLIN PRODUCTION AFTER INHIBITION BY LOW-DOSES OF ASPIRIN [J].

JAFFE, EA ;

WEKSLER, BB .

JOURNAL OF CLINICAL INVESTIGATION, 1979, 63 (03) :532-535

[14] HYDROLYSIS OF ASPIRIN BY RAT SMALL INTESTINE [J].

LEVY, G ;

ANGELINO, NJ .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1968, 57 (08) :1449-&

[15] CLINICAL PHARMACOKINETICS OF SALICYLATES - A REASSESSMENT [J].

LEVY, G .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1980, 10 :S285-S290

[16] ARACHIDONATE METABOLISM IN VASCULAR DISORDERS [J].

MAJERUS, PW .

JOURNAL OF CLINICAL INVESTIGATION, 1983, 72 (05) :1521-1525

[17] SALICYLATE REVERSES INVITRO ASPIRIN INHIBITION OF RAT PLATELET AND VASCULAR PROSTAGLANDIN GENERATION [J].

MERINO, J ;

LIVIO, M ;

RAJTAR, G ;

DEGAETANO, G .

BIOCHEMICAL PHARMACOLOGY, 1980, 29 (08) :1093-1096

[18]

METZLER CM, 1969, NONLIN7292697293005

[19] EVALUATION OF ACETYLSALICYLIC ACID ESTERASE IN ASPIRIN METABOLISM - INTERSPECIES COMPARISON [J].

MORGAN, AM ;

TRUITT, EB .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1965, 54 (11) :1640-+

[20] PHARMACOKINETIC ANALYSIS AND CALCULATIONS USING A PROGRAM FOR THE MINICALCULATOR TI-59 [J].

NIELSENKUDSK, F .

INTERNATIONAL JOURNAL OF BIO-MEDICAL COMPUTING, 1981, 12 (01) :83-96

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