INTERACTION OF 9-AMINO-1,2,3,4-TETRAHYDROAMINO-ACRIDINE (THA) WITH HUMAN CORTICAL NICOTINIC AND MUSCARINIC RECEPTOR-BINDING INVITRO

被引：78

作者：

PERRY, EK

SMITH, CJ

COURT, JA

BONHAM, JR

RODWAY, M

ATACK, JR

机构：

[1] NEWCASTLE GEN HOSP,DEPT NEUROPATHOL,NEWCASTLE TYNE NE4 6BE,TYNE & WEAR,ENGLAND

[2] NEWCASTLE GEN HOSP,DEPT CLIN BIOCHEM,NEWCASTLE TYNE NE4 6BE,TYNE & WEAR,ENGLAND

[3] NIH,DEPT HLTH & HUMAN SERV,BETHESDA,MD 20205

来源：

NEUROSCIENCE LETTERS | 1988年 / 91卷 / 02期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/0304-3940(88)90770-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

引用

页码：211 / 216

页数：6

共 14 条

[1]

ATACK JR, 1986, J NEUROCHEM, V47, P263

[2] ACETYLCHOLINESTERASE AND BUTYRYLCHOLINESTERASE MEASUREMENT IN THE PRENATAL DETECTION OF NEURAL-TUBE DEFECTS AND OTHER FETAL MALFORMATIONS [J].

BONHAM, JR ;

GOWENLOCK, AH ;

TIMOTHY, JAD .

CLINICA CHIMICA ACTA, 1981, 115 (02) :163-170

[3] RAISING THE AMBIENT POTASSIUM-ION CONCENTRATION ENHANCES CARBACHOL STIMULATED PHOSPHOINOSITIDE HYDROLYSIS IN RAT-BRAIN HIPPOCAMPAL AND CEREBRAL CORTICAL MINIPRISMS [J].

COURT, JA ;

FOWLER, CJ ;

CANDY, JM ;

HOBAN, PR ;

SMITH, CJ .

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1986, 334 (01) :10-16

[4] 9-AMINO-1,2,3,4-TETRAHYDROACRIDINE (THA), AN ALLEGED DRUG FOR THE TREATMENT OF ALZHEIMERS-DISEASE, INHIBITS ACETYLCHOLINESTERASE ACTIVITY AND SLOW OUTWARD K+ CURRENT [J].

DRUKARCH, B ;

KITS, KS ;

VANDERMEER, EG ;

LODDER, JC ;

STOOF, JC .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1987, 141 (01) :153-157

[5] CHOLINERGIC APPROACHES TO THE TREATMENT OF ALZHEIMERS-DISEASE [J].

HOLLANDER, E ;

MOHS, RC ;

DAVIS, KL .

BRITISH MEDICAL BULLETIN, 1986, 42 (01) :97-100

[6] ACETYLCHOLINESTERASE GENERATES ENKEPHALIN-LIKE IMMUNOREACTIVITY WHEN IT DEGRADES THE SOLUBLE-PROTEINS (CHROMOGRANINS) FROM ADRENAL CHROMAFFIN GRANULES [J].

ISMAEL, Z ;

MILLAR, TJ ;

SMALL, DH ;

CHUBB, IW .

BRAIN RESEARCH, 1986, 376 (02) :230-238

[7] ENZYME INHIBITING ACTION OF TETRAHYDROAMINOACRIDINE AND ITS STRUCTURAL FRAGMENTS [J].

KAUL, PN .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1962, 14 (04) :243-&

[8] DO TETRAHYDROAMINOACRIDINE (THA) AND PHYSOSTIGMINE RESTORE ACETYLCHOLINE-RELEASE IN ALZHEIMER BRAINS VIA NICOTINIC RECEPTORS [J].

NILSSON, L ;

ADEM, A ;

HARDY, J ;

WINBLAD, B ;

NORDBERG, A .

JOURNAL OF NEURAL TRANSMISSION, 1987, 70 (3-4) :357-368

[9] 9-AMINO-1,2,3,4-TETRAHYDROACRIDINE (THA) IS A POTENT BLOCKER OF CARDIAC POTASSIUM CHANNELS [J].

OSTERRIEDER, W .

BRITISH JOURNAL OF PHARMACOLOGY, 1987, 92 (03) :521-525

[10]

PERRY EK, 1986, CAN J NEUROL SCI, V13, P521

← 1 2 →