GENE ENCODING THE COLLAGEN TYPE-I AND THROMBOSPONDIN RECEPTOR CD36 IS LOCATED ON CHROMOSOME-7Q11.2

被引：50

作者：

FERNANDEZRUIZ, E

ARMESILLA, AL

SANCHEZMADRID, F

VEGA, MA

机构：

[1] HOSP PRINCESA,UNIDAD BIOL MOLEC,PLANTA 9,C DIEGO LEON 62,E-28006 MADRID,SPAIN

[2] HOSP PRINCESA,DEPT INMUNOL,E-28006 MADRID,SPAIN

来源：

GENOMICS | 1993年 / 17卷 / 03期

关键词：

D O I：

10.1006/geno.1993.1401

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The human CD36 is a member of a gene family of structurally related glycoproteins and functions as a receptor for collagen type I and thrombospondin. CD36 also binds to red blood cells infected with the human malaria parasite Plasmodium falciparum. In the present study, the CD36 gene was assigned to chromosome 7 by using the polymerase chain reaction with DNA from human-hamster somatic cell hybrids. Furthermore, the use of a CD36 genomic probe has allowed the localization of the CD36 locus to the 7q11.2 band by fluorescence in situ hybridization coupled with GTG-banding. © 1993 Academic Press, Inc.

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页码：759 / 761

页数：3

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