TUBULOINTERSTITIAL NEPHRITIS AND UVEITIS - AN IMMUNOLOGICAL DISORDER

被引：31

作者：

BIRNBACHER, R

BALZAR, E

AUFRICHT, C

SCHMALDIENST, S

WOLOSZCZUK, W

FORSTER, E

机构：

[1] Department of Paediatrics, University of Vienna, Vienna, A-1090

[2] Department of Internal Medicine III, University of Vienna, Vienna, A-1090

[3] Department of Ludwig Boltzmann Institute of Experimental Endocrinology, University of Vienna, Vienna, A-1090

来源：

PEDIATRIC NEPHROLOGY | 1995年 / 9卷 / 02期

关键词：

TINU SYNDROME; TUBULOINTERSTITIAL NEPHRITIS; UVEITIS; T-CELL ACTIVATION; TOPICAL STEROIDS;

D O I：

10.1007/BF00860744

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A 14-year-old boy with tubulointerstitial nephritis and uveitis (TINU syndrome) is described. Nephropathy improved without systemic cortisone treatment, whereas uveitis relapsed and was treated with topical steroids. Blood cell immunological analysis and serum analysis revealed signs of cytotoxic T-cell, macrophage and granulocyte activation, which declined as the clinical symptoms improved. This may be interpreted as an indication of their significance as markers in the pathogenesis of this syndrome or as part of a microbial-triggered immune response.

引用

页码：193 / 195

页数：3