THE TELOMERE HYPOTHESIS OF CELLULAR AGING

被引：419

作者：

HARLEY, CB

VAZIRI, H

COUNTER, CM

ALLSOPP, RC

机构：

[1] Department of Biochemistry, McMaster University, Hamilton

来源：

EXPERIMENTAL GERONTOLOGY | 1992年 / 27卷 / 04期

关键词：

TELOMERES; CELL AGING; REPLICATIVE SENESCENCE; HAYFLICK LIMIT;

D O I：

10.1016/0531-5565(92)90068-B

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

[No abstract available]

引用

页码：375 / 382

页数：8

共 13 条

[1]

ALLSOPP RC, UNPUB TELOMERE LENGT

[2] STRUCTURE AND FUNCTION OF TELOMERES [J].

BLACKBURN, EH .

NATURE, 1991, 350 (6319) :569-573

[3] TELOMERE SHORTENING ASSOCIATED WITH CHROMOSOME INSTABILITY IS ARRESTED IN IMMORTAL CELLS WHICH EXPRESS TELOMERASE ACTIVITY [J].

COUNTER, CM ;

AVILION, AA ;

LEFEUVRE, CE ;

STEWART, NG ;

GREIDER, CW ;

HARLEY, CB ;

BACCHETTI, S .

EMBO JOURNAL, 1992, 11 (05) :1921-1929

[4] REPLICATIVE SENESCENCE - THE HUMAN FIBROBLAST COMES OF AGE [J].

GOLDSTEIN, S .

SCIENCE, 1990, 249 (4973) :1129-1133

[5] A TELOMERIC SEQUENCE IN THE RNA OF TETRAHYMENA TELOMERASE REQUIRED FOR TELOMERE REPEAT SYNTHESIS [J].

GREIDER, CW ;

BLACKBURN, EH .

NATURE, 1989, 337 (6205) :331-337

[6] TELOMERES SHORTEN DURING AGING OF HUMAN FIBROBLASTS [J].

HARLEY, CB ;

FUTCHER, AB ;

GREIDER, CW .

NATURE, 1990, 345 (6274) :458-460

[7]

HARLEY CB, IN PRESS MUTAT RES

[8] LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS [J].

HAYFLICK, L .

EXPERIMENTAL CELL RESEARCH, 1965, 37 (03) :614-&

[9] SERIAL CULTIVATION OF HUMAN DIPLOID CELL STRAINS [J].

HAYFLICK, L ;

MOORHEAD, PS .

EXPERIMENTAL CELL RESEARCH, 1961, 25 (03) :585-+

[10]

LEVY MA, J MOL BIOL, V225, P951

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