VIRUCIDAL EFFECTS OF THE STEAM DISTILLATE FROM HOUTTUYNIA-CORDATA AND ITS COMPONENTS ON HSV-1, INFLUENZA-VIRUS, AND HIV

被引：162

作者：

HAYASHI, K ^{[1
]}

KAMIYA, M ^{[1
]}

HAYASHI, T ^{[1
]}

机构：

[1] TOYAMA MED & PHARMACEUT UNIV,FAC PHARMACEUT SCI,TOYAMA 93001,JAPAN

来源：

PLANTA MEDICA | 1995年 / 61卷 / 03期

关键词：

HOUTTUYNIA CORDATA THUNB; SAURURACEAE; ANTIVIRAL ACTIVITY; METHYL N-NONYL KETONE; LAURYL ALDEHYDE; CAPRYL ALDEHYDE;

D O I：

10.1055/s-2006-958063

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The steam distillate prepared from fresh plants of Houttuynia cordata Thunb. (Saururaceae) was found to have direct inhibitory activity against herpes simplex virus type 1 (HSV-1), influenza virus, and human immunodeficiency virus type 1 (HIV-1) without showing cytotoxicity, but not against poliovirus and coxsackievirus. The loss of viral infectivity was related to the duration of drug treatment, Three major components of the distillate, methyl n-nonyl ketone, lauryl aldehyde, and capryl aldehyde, also inactivated HSV-1, influenza virus, and HIV-1. These in vitro findings demonstrate that the essential oils provide virucidal activity against enveloped viruses by interfering with the function of virus envelope.

引用

页码：237 / 241

页数：5

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