ANTIMICROBIAL SUSCEPTIBILITIES OF A CORYNEBACTERIUM CDC GROUP-I1 STRAIN ISOLATED FROM A PATIENT WITH ENDOCARDITIS

被引：10

作者：

MALANOSKI, GJ

PARKER, R

ELIOPOULOS, GM

机构：

[1] NEW ENGLAND DEACONESS HOSP,DIV INFECT DIS,BOSTON,MA 02215

[2] NEW ENGLAND DEACONESS HOSP,DEPT MED,DIV GEN INTERNAL MED,BOSTON,MA 02215

[3] HARVARD UNIV,SCH MED,BOSTON,MA 02115

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1992年 / 36卷 / 06期

关键词：

D O I：

10.1128/AAC.36.6.1329

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We encountered a case of native valve endocarditis due to Corynebacterium CDC group 11 which was successfully controlled with antimicrobial agents alone. This organism and three other isolates of this group were susceptible to penicillin, vancomycin, and gentamicin. The combination of penicillin with subinhibitory concentrations of gentamicin resulted in a 1,000-fold decrease in CFU per milliliter at 24 h compared with penicillin alone. Augmentation of killing was noted also with vancomycin plus gentamicin but to a degree that did not meet strict criteria for bactericidal synergism.

引用

页码：1329 / 1331

页数：3