SYNTHESIS OF POLYFUNCTIONAL GAMMA-LACTAMS AND PERHYDRO-1,2-PYRIDAZIN-3-ONES

被引：23

作者：

AMRI, H ^{[1
]}

ELGAIED, MM ^{[1
]}

BENAYED, T ^{[1
]}

VILLIERAS, J ^{[1
]}

机构：

[1] FAC SCI & TECHN NANTES,CNRS,SYNTHESE ORGAN LAB,F-44072 NANTES 03,FRANCE

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 48期

关键词：

AMINES; HYDRAZINES; ALPHA-(HYDROXYALKYL)ACRYLONITRILES; CONJUGATED ADDITION; ALPHA; BETA-DIFUNCTIONALIZED GAMMA-BUTYROLACTAMES; POLYFUNCTIONALIZED PERHYDRO-1,2-PYRIDAZIN-3-ONES;

D O I：

10.1016/S0040-4039(00)60183-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Direct condensation, in methanol, of primary amines on 2-(1-carbethoxy-1-hydroxyethyl)acrylonitrile yielded to alpha and beta-functionalized gamma-lactames 6(a-f). The same reaction with hydrazines gave perhydro-1,2-pyridazin-3-ones 7 and 8 when nitrogen is not dialkylated.

引用

页码：7345 / 7346

页数：2

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