SYNTHESIS OF (+/-)-1'-AZA-CARBOCYCLIC-PYRIMIDINE-2',3'-DIDEOXYNUCLEOSIDE ANALOGS AS POTENTIAL ANTI-HIV AGENTS

被引:22
作者
MANSOUR, TS
JIN, H
机构
[1] Medicinal Chemistry Division, IAF BioChem International Inc., Laval, Que. H7V 1B7
关键词
D O I
10.1016/S0960-894X(01)81063-5
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
1'-Aza-carbocyclic-2',3'-dideoxyuridine, 3'-deoxythymidine and 2',3'-dideoxycytidine were synthesized from 1-aminopyrrolidine intermediate 13 and evaluated as anti-HIV agents in MT-4 cells.
引用
收藏
页码:757 / 760
页数:4
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