SYNTHESIS OF (+/-)-1'-AZA-CARBOCYCLIC-PYRIMIDINE-2',3'-DIDEOXYNUCLEOSIDE ANALOGS AS POTENTIAL ANTI-HIV AGENTS

被引：22

作者：

MANSOUR, TS

JIN, H

机构：

[1] Medicinal Chemistry Division, IAF BioChem International Inc., Laval, Que. H7V 1B7

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1991年 / 1卷 / 12期

关键词：

D O I：

10.1016/S0960-894X(01)81063-5

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

1'-Aza-carbocyclic-2',3'-dideoxyuridine, 3'-deoxythymidine and 2',3'-dideoxycytidine were synthesized from 1-aminopyrrolidine intermediate 13 and evaluated as anti-HIV agents in MT-4 cells.

引用

页码：757 / 760

页数：4

共 17 条

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