SCANNING FORCE MICROSCOPY ON LIVE CULTURED-CELLS - IMAGING AND FORCE-VERSUS-DISTANCE INVESTIGATIONS

被引：23

作者：

RICCI, D

GRATTAROLA, M

机构：

[1] Dipartimento di Ingegneria Biofisica ed Elettronica, Università di Genova, Genova, 16145

来源：

JOURNAL OF MICROSCOPY-OXFORD | 1994年 / 176卷

关键词：

SCANNING FORCE MICROSCOPE; SFM; AFM; LIVE CULTURED CELLS; FORCE-VERSUS-DISTANCE; CURVE; INDENTATION;

D O I：

10.1111/j.1365-2818.1994.tb03523.x

中图分类号：

TH742 [显微镜];

学科分类号：

摘要：

Extensive measurements with the scanning force microscope on living cells in their native liquid environment are described with the purpose of critically assessing the extent of the interaction between the SFM tip and the (soft) cell materials and the effect of such interaction on topographic information. Images are obtained under various force conditions and systematically correlated with force-versus-distance curves. As a result, detailed indications about tip indentation are given, thickness estimates deduced and identification of submembranous cytoplasmic structures suggested.

引用

页码：254 / 261

页数：8

共 14 条

[1] VIDEO-ENHANCED CONTRAST, DIFFERENTIAL INTERFERENCE CONTRAST (AVEC-DIC) MICROSCOPY - A NEW METHOD CAPABLE OF ANALYZING MICROTUBULE-RELATED MOTILITY IN THE RETICULOPODIAL NETWORK OF ALLOGROMIA LATICOLLARIS [J].