SOLID-PHASE SYNTHESIS OF GLYCOPEPTIDES - GLYCOSYLATION OF RESIN-BOUND SERINE-PEPTIDES BY 3,4,6-TRI-O-ACETYL-D-GLUCOSE-OXAZOLINE

被引：50

作者：

HOLLOSI, M

KOLLAT, E

LACZKO, I

MEDZIHRADSZKY, KF

THURIN, J

OTVOS, L

机构：

[1] EOTVOS LORAND UNIV, DEPT ORGAN CHEM, H-1364 BUDAPEST 5, HUNGARY

[2] UNIV CALIF SAN FRANCISCO, DEPT PHARMACEUT CHEM, SAN FRANCISCO, CA 94143 USA

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 12期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

D O I：

10.1016/S0040-4039(00)74264-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3, 4, 6-Tri-O-acetyl-D-glucose-oxazoline, prepared from 2-acetamido-2-deoxy-1, 3, 4, 6-tetra-O-acetyl-beta-D-glucopyranose with trimethylsilyl trifluoromethanesulfonate, was used for O-glycosylating resin-bound protected peptides having a serine residue with free hydroxyl group. 2-acetamido-2-deoxy-D-glucopyranosyl peptides were obtained after trifluoracetic acid (TFA) cleavage and deacetylation.

引用

页码：1531 / 1534

页数：4

共 22 条

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