QUINOLINIC ACID CONCENTRATIONS IN STRIATAL EXTRACELLULAR FLUID REACH POTENTIALLY NEUROTOXIC LEVELS FOLLOWING SYSTEMIC L-TRYPTOPHAN LOADING

被引：51

作者：

DURING, MJ

HEYES, MP

FREESE, A

MARKEY, SP

MARTIN, JB

ROTH, RH

机构：

[1] MASSACHUSETTS GEN HOSP, DEPT NEUROL, BOSTON, MA 02114 USA

[2] HARVARD UNIV, SCH MED, BOSTON, MA 02114 USA

[3] NIMH, ANALYT BIOCHEM SECT, CLIN SCI LAB, BETHESDA, MD 20892 USA

[4] MIT, DIV HLTH SCI & TECHNOL, CAMBRIDGE, MA 02139 USA

[5] YALE UNIV, SCH MED, DEPT PSYCHIAT, NEW HAVEN, CT 06510 USA

来源：

BRAIN RESEARCH | 1989年 / 476卷 / 02期

关键词：

D O I：

10.1016/0006-8993(89)91265-1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

引用

页码：384 / 387

页数：4

共 29 条

[11] (O-18)QUINOLINIC ACID - ITS ESTERIFICATION WITHOUT BACK EXCHANGE FOR USE AS INTERNAL STANDARD IN THE QUANTIFICATION OF BRAIN AND CSF QUINOLINIC ACID [J].

HEYES, MP ;

MARKEY, SP .

BIOMEDICAL AND ENVIRONMENTAL MASS SPECTROMETRY, 1988, 15 (05) :291-293

[12]

HEYES MP, 1987, SOC NEUR ABSTR, V13, P453

[13]

KNOX WE, 1951, BRIT J EXP PATHOL, V32, P462

[14]

LAPIN IP, 1982, J NEURAL TRANSM, V54, P229, DOI 10.1007/BF01254932

[15] EFFECTS OF PRECURSOR LOADING IN CEREBRAL METABOLISM OF 5-HYDROXYINDOLES [J].

MOIR, ATB ;

ECCLESTO.D .

JOURNAL OF NEUROCHEMISTRY, 1968, 15 (10) :1093-+

[16] PRESENCE OF KYNURENIC ACID IN THE MAMMALIAN BRAIN [J].

MORONI, F ;

RUSSI, P ;

LOMBARDI, G ;

BENI, M ;

CARLA, V .

JOURNAL OF NEUROCHEMISTRY, 1988, 51 (01) :177-180

[17] THE EXCITOTOXIN QUINOLINIC ACID IS PRESENT AND UNEVENLY DISTRIBUTED IN THE RAT-BRAIN [J].

MORONI, F ;

LOMBARDI, G ;

CARLA, V ;

MONETI, G .

BRAIN RESEARCH, 1984, 295 (02) :352-355

[18] CONTENT OF QUINOLINIC ACID AND OF OTHER TRYPTOPHAN-METABOLITES INCREASES IN BRAIN-REGIONS OF RATS USED AS EXPERIMENTAL-MODELS OF HEPATIC-ENCEPHALOPATHY [J].

MORONI, F ;

LOMBARDI, G ;

CARLA, V ;

PELLEGRINI, D ;

CARASSALE, GL ;

CORTESINI, C .

JOURNAL OF NEUROCHEMISTRY, 1986, 46 (03) :869-874

[19]

NICHOLSON C, 1980, NEUROSCI RES PROG B, V18, P177

[20]

Paxinos G., 2007, RAT BRAIN STEREOTAXI, V6th ed.

← 1 2 3 →