CRYSTAL-STRUCTURES OF ALPHA-FUNALTREXAMINE AND BETA-FUNALTREXAMINE - CONFORMATIONAL REQUIREMENT OF THE FUMARAMATE MOIETY IN THE IRREVERSIBLE BLOCKAGE OF MU-OPIOID RECEPTORS

被引：28

作者：

GRIFFIN, JF ^{[1
]}

LARSON, DL ^{[1
]}

PORTOGHESE, PS ^{[1
]}

机构：

[1] UNIV MINNESOTA,COLL PHARM,DEPT MED CHEM,MINNEAPOLIS,MN 55455

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1986年 / 29卷 / 05期

关键词：

D O I：

10.1021/jm00155a031

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：778 / 783

页数：6

共 23 条

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[8] CRYSTAL STRUCTURES OF DL-CYCLAZOCINE AND L-CYCLAZOCINE.HBR.H2O, AND ABSOLUTE CONFIGURATION OF L-CYCLAZOCINE.HBR.H20(2-CYCLOPROPYLMETHYL-2'-HYDROXY-5,9-DIMETHYL-6,7-BENZOMORPHAN)
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[J]. ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL CRYSTALLOGRAPHY AND CRYSTAL CHEMISTRY, 1969, B 25 : 1469 - &
[9] NOVEL OPIOID RECEPTOR-SITE DIRECTED ALKYLATING AGENT WITH IRREVERSIBLE NARCOTIC ANTAGONISTIC AND REVERSIBLE AGONISTIC ACTIVITIES
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[10] PORTOGHESE PS, 1984, NATURAL PRODUCTS DRU, P421

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